Lesofavumab
- Product NameLesofavumab
- CAS1807960-57-1
- CBNumberCB98081024
- MW0
- MOL FileMol file
- MSDS FileSDS
Lesofavumab Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| ChemScene CS-0628953 | 1mg | $325 | Lesofavumab 98.27% |
Buy |
| ChemScene CS-0628953 | 5mg | $845 | Lesofavumab 98.27% |
Buy |
| ChemScene CS-0628953 | 10mg | $1354 | Lesofavumab 98.27% |
Buy |
| ApexBio Technology BA2024 | 1mg | $270 | Lesofavumab |
Buy |
| ApexBio Technology BA2024 | 5mg | $702 | Lesofavumab |
Buy |
Lesofavumab Chemical Properties,Usage,Production
Uses
Lesofavumab (MHAB5553A) is a human IgG1κ anti-influenza B virus antibody[1].in vivo
Lesofavumab (46B8; 15 mg/kg; i.v.; single dose) is able to protect mice against lethal challenge of the mutant influenza B virus[2].
| Animal Model: | DBA/2J mice, B/Wisconsin/1/2010, B/Brisbane/60/2008, B/Victoria/504/2000, B/Russia/1/1969 or B/Massachusetts/3/1966 infection model[2] |
| Dosage: | 15 mg/kg |
| Administration: | Intravenous administration, single dose, 24, 48 or 72h post infection |
| Result: | Treatment at 24 and 48 h post infection resulted in 100% protection, with the only exception of mice infected with B/Russia/1/1969 that showed a 60% protection when treatment commenced at 48h. Even when given at 72h post infection, 48B8 was highly efficacious resulting in 100% protection against the B/Brisbane/60/2008, B/Victoria/504/2000 and B/Massachusetts/3/1966 strains, 75% protection against B/Wisconsin/1/2010 and 50% protection against B/Russia/1/1969. |
References
[1] Rao GK, et al. In Vivo Assessment of Antibody-Dependent Enhancement of Influenza B Infection. Toxicol Sci. 2019 Jun 1;169(2):409-421. DOI:10.1093/toxsci/kfz053[2] Chai N, et al. A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action. Nat Commun. 2017 Jan 19;8:14234. DOI:10.1038/ncomms14234
Preparation Products And Raw materials
Lesofavumab Suppliers
Global(16)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 177-54423994 17754423994 |
2853530910@QQ.com | China | 7996 | 62 | |
| 15817493340 | 981810490@qq.com | China | 1577 | 58 | |
| 027-65317797 15926423062 |
422450190@qq.com | China | 10302 | 58 | |
| 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 | |
| 027-65279366 18108604356 |
products@biolabreagent.com | China | 9864 | 58 | |
| 13720134139 086-15871494362 13720134139 |
orders@jknbiochem.com | China | 7284 | 58 | |
| 021-65675885 18964387627 |
customer_service@efebio.com | China | 11963 | 58 | |
| 027-027-16602739303 16602739303 |
673003916@qq.com | China | 4622 | 58 | |
| 15111215862 18229892877 |
3062105966@qq.com | China | 5571 | 58 | |
| 0573-83568680 18057391398 |
3956524501@qq.com | China | 1441 | 58 |
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