Uses
Zymosterone is analyzed in enzymatic studies such as its conversion from zymosterone to zymosterol using an enzyme, HSD17B7, and a cofactor, reduced NADP.
Definition
ChEBI: Zymosterol intermediate 2 is a 3-oxo steroid. It has a role as a human metabolite and a Saccharomyces cerevisiae metabolite. It derives from a hydride of a 5alpha-cholestane.
Biological Activity
Zymosterone is metabolized to cholesterol synthesis intermediate, zymosterol in the presence of enzyme hydroxysteroid (17β) dehydrogenase 7 (HSD17B7). Zymosterone conversion to zymosterol catalyzed by 3-keto sterol reductase (ERG27) is a key step in yeast ergosterol biosynthesis.
