2,4,6,8,10,12,14-Hexadecaheptaenediamide,N,N'-bis(2-hydroxy-5-oxo-1-cyclopenten-1-yl)-, (2E,4E,6E,8E,10E,12E,14E)- (9CI)

Description

Limocrocin is a reverse transcriptase inhibitor.

Uses

Limochromin is a pigment produced by Streptomyces limosus that strongly inhibits the reverse transcriptase of avian myeloid leukemia virus (AMV). The inhibitory activity of limochromin is not affected by changes in the concentration of template-primer, substrate or carrier protein, but its inhibitory effect is significantly reduced when the concentration of AMV reverse transcriptase increases. Limochromin can be used to develop antiviral treatments[1].

References

[1] HANAJIMA S, et al. Inhibition of reverse transcriptase by limocrocin[J]. The Journal of antibiotics, 1985, 38(6): 803-805. DOI:10.7164/antibiotics.38.803