Description
5-(3-AMino-1-propyn-1-yl)-2'-deoxyuridine 5'-(Tetrahydrogen Triphosphate), also known as 5-PA-dUTP or 5-Propargylamino-dUTP, is a C5-modified nucleotide and can be incorporated into DNA nanoparticles (DNPs) for photosensitizer delivery. 5-PA-dUTP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Uses
5-(3-Amino-1-propyn-1-yl)-2''-deoxyuridine 5''-(Tetrahydrogen Triphosphate) is an intermediate in the synthesis of Texas Red-5-dUTP (T320100), a fluorescence-labelled nucleotide analog. Texas Red-5-dUTP is used diagnostically for detection of rearranged SS18 in formalin-fixed, paraffin-embedded synovial sarcoma.
