(6aS)-5,6,6a,7-Tetrahydro-1,10-dimethoxy-4H-dibenzo[de,g]quinoline-2,11-diol

Description

The roots of Lindera pipericarpa Boer!. yield this noraporphine alkaloid which, on recrystallization from AcOEt, forms colourless, slender needles. The base has [α]²²_D + 166° (c 1.35, EtOH) and yields a hydrochloride crystallizing from aqueous EtOH, m.p. 200°C (dec.) and the N-methyl derivative, m.p. 196°C; [α]²²_D + 222° (c 0.8, MeOH). The O,N-dimethyl compound is identical with Isocorydine (q.v.).

References

Kiang, Sim., J. Chem. Soc., C, 282 (1967)