2,2'-BIS(ETHOXYCARBONYL)-1-O-[(DIISOPROPYLAMINO)(2-CYANOETHOXY)PHOSPHINO]-3-O-[4,4'-DIMETHOXY-4''-(1H,1H,2H,2H-PERFLUORODECYL)TRITYL]-1,3-PROPANEDIOL

Uses

F-CPR-II CEP allows a combination of fluorous affinity purification with concomitant 5''-phosphorylation, which is especially attractive when synthesizing longmers that will be used in ligase reactions. It may also be utilized as a common handle for fluorous purification, obviating the need to choose a different fluorous phosphoramidite for each different 5''-terminal nucleotide when a 5''-phosphate is tolerated in a particular application.