Uses
Cytosine-13C,15N2 is the 13C and 15N labeled Cytosine[1]. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging[2][3].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:
10.1177/1060028018797110[2] Maxam AM, et, al. A new method for sequencing DNA. Proc Natl Acad Sci U S A. 1977 Feb;74(2):560-4. DOI:
10.1073/pnas.74.2.560[3] Oh G, et, al. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Nat Commun. 2018 Feb 139(1):644. DOI:
10.1038/s41467-018-03073-7[4] Nucleotide Biosynthesis Process[J]. Definitions, 2020, 30 1. DOI:
10.32388/28chil[5] ACHIM BREILING Frank L. Epigenetic regulatory functions of DNA modifications: 5-methylcytosine and beyond.[J]. Epigenetics & Chromatin, 2015, 8: 24. DOI:
10.1186/s13072-015-0016-6
