Description
SB-734117 is a novel potent MSK-1 inhibitor, inhibiting replication of HCMV strain AD169.
Uses
SB-734117 is a human cytomegalovirus (HCMV) replication inhibitor that prevents CREB and histone H3 post-translational modifications[1].
References
[1] Amina S Khan, et al. High-throughput screening of a GlaxoSmithKline protein kinase inhibitor set identifies an inhibitor of human cytomegalovirus replication that prevents CREB and histone H3 post-translational modification. J Gen Virol. 2017 Apr;98(4):754-768. DOI:
10.1099/jgv.0.000713