Uses
Anti-GNB2L1 antibody produced in rabbit is suitable for indirect ELISA and western blot applications.
General Description
Guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 (GNB2L1) is a stably expressed housekeeping gene expressed in alveolar macrophage and neutrophils. The gene is hypothesized to encode a protein RACK1 (Receptor for activated C kinase 1). It is mapped on the telomeric position of chromosome 5q35.3.
Biochem/physiol Actions
Guanine nucleotide binding protein (G protein), β polypeptide 2-like 1 (GNB2L1) is a scaffold protein highly involved in the binding and anchorage of protein kinase C. It has been hypothesized that GNB2L1 may act as a regulatory cofactor of multidrug resistance protein 3 (MDR3/ABCB4) and is vital for the plasma membrane localization and for mediating translocation function of ABCB4.
