Description
1,2-Dipalmitoyl-3-linoelaidoyl-
rac-glycerol is a triacylglycerol that contains palmitic acid at the
sn-1 and
sn-2 positions and linoelaidic acid at the
sn-3 position.
Uses
12-Dipalmitoyl-3-Linoelaidoyl-rac-glycerol is a triacylglycerol containing palmitic acid (HY-N0830) at the sn-1 and sn-2 positions and linoelaidic acid (HY-W071746) at the sn-3 position. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. Palmitic acid can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells. Linolelaidic acid, an omega-6 trans fatty acid, acts as a source of energy. Linolelaidic acid is an essential nutrient, adding in enteral, parenteral, and infant formulas. Linolelaidic acid can be used for heart diseases research[1][2][3].
Definition
ChEBI: Glycerol 1,2-dihexadecanoate 3-(9Z,12Z-octadecadienoate) is a triglyceride.
References
[1] Harada H, et al. Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga. Anticancer Res. 2002 Sep-Oct;22(5):2587-90. PMID:12529968
[2] Ding WJ, et al. Expression of Notch family is altered in nonalcoholic fatty liver disease. Mol Med Rep. 2020 Sep;22(3):1702-1708. DOI:
10.3892/mmr.2020.11249[3] Whelan J, et al. Linoleic acid. Adv Nutr. 2013 May 1;4(3):311-2. DOI:
10.3945/an.113.003772
