Uses
A hydroxamate-based inhibitor of MMPs and TACE
Uses
N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide is a TACE inhibitor. Inhibits the secretase in pig kidney microvillar membranes.
Definition
ChEBI: N-[2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide Acetic Acid is a dipeptide.
Biological Activity
Cell permeable: no', 'Primary Target
MMPs', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 18 μM against angiotensin converting enzyme
