Uses
2-Nitrophenylacetic Acid is a useful research chemical.
Chemical Properties
yellow to beige crystalline powder
Uses
2-Nitrophenylacetic acid was used as an internal standard in the determination of the theophylline solubilizer salicylamide-O-acetic acid.
Definition
ChEBI: (2-nitrophenyl)acetic acid is a member of the class of phenylacetic acids that is phenylacetic acid in which the phenyl grup is substituted at the ortho- position by a nitro group. It is a C-nitro compound and a member of phenylacetic acids. It is functionally related to a nitrobenzene and a phenylacetic acid.
Safety Profile
Mutation data reported. Forms an explosive mixture with thionyl chloride. When heated to decomposition it emits toxic fumes of NOx.
Purification Methods
The acid crystallises as yellow needles from EtOH, EtOH/water and dry it over P2O5 under vacuum. The amide has m 160-161o (from *C6H6 plates or EtOH, needles). [Beilstein 9 III 2282, 9 IV 1687.]
