Definition
ChEBI: Lymphostin is a member of the class of pyrroloquinolines that is pyrrolo[4,3,2-de]quinoline in which the hydrogens at positions 4, 6 and 8 are replaced by (1E)-1-methoxy-3-oxoprop-1-en-3-yl, acetylamino and amino groups, respectively. It is an alkaloid isolated from Streptomyces and Salinispora species, exhibits potent immunosuppressive activity, and inhibits Fyn and Lck protein kinases. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor, an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor, an immunosuppressive agent, a bacterial metabolite and a marine metabolite. It is a pyrroloquinoline, an alkaloid, a member of acetamides, a primary arylamine, an enol ether and an enone.
