Uses
Monoclonal Anti-Titin antibody produced in mouse has been used in following studies.
- western blotting
- antibody staining
- immunofluorescence microscopy
- immunohistochemistry
General Description
Monoclonal Anti-Titin (mouse IgG2b isotype) is derived from the hybridoma produced by the fusion of mouse myeloma cells and splenocytes from an immunized mouse. It is a flexible, filamentous constituent of striated muscle that is thought to give rise to an elastic filament component underlying the myofibrillar organization.
Biochem/physiol Actions
Monoclonal Anti-Titin can be used for study of the elastic filaments within sarcomeric structures. It is also useful as a differentiation marker in the separation of rhabdomyosarcomas from other muscle tumors.
