Uses
Anti-PAR4 antibody produced in rabbit has been used in immunoblotting (1:1000).
General Description
Anti-Prostate Apoptosis Response protein-4 Antibody detects endogenous levels of total Prostate Apoptosis Response protein-4 protein.
Biochem/physiol Actions
Protease-activated receptor 4 (PAR4) protein is involved in vascular inflammation. It is necessary for a stable thrombus as it mediates persistent thrombin signaling in platelets. PAR4 aids pro-inflammatory actions by interacting with the bradykinin B2 receptor. It is linked to renal function and the development of chronic kidney disease (CKD).
