Description
A further alkaloid isolated from Vinca minor L., this base is possibly optically
inactive, the specific rotation reported being [α]
D 00 ± 2° (c 1.0, EtOH). The
ultraviolet spectrum in EtOH has a broad absorption maximum at 338 mil and
an inflexion at 310 mil. The structure has been confirmed by the synthesis of the
(±)-form.
References
Kokry, Dubravkova, Sefecovic.,Experientia, 18,564 (1962)
Mokryetal., ibid, 19,311 (1963)
Zachystalova, Strouf, Trojanek., Chern. & Ind., 610 (1963)
Synthesis:
Kutney et al., J. Amer. Chern. Soc., 90,3891 (1968)
