(S) QuinoxP(R)

Reaction

1. Ligand for the rhodium-catalyzed, asymmetric hydrogenation of dehydroamino acid esters and α-enamides.
2. Ligand for the rhodium-catalyzed, asymmetric 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds.
3. Ligand for the rhodium-catalyzed, asymmetric alkylative ring opening reaction
4. Ligand for the palladium-catalyzed asymmetric allylic alkylation and amination of racemic substrates.
5. Ligand for the ruthenium-catalyzed asymmetric hydrogenation of ketones.
6. Ligand for the rhodium-catalyzed, asymmetric hydroacylation of 1,1-disubstituted alkenes with aldehydes.
7. Ligand for the silver-catalyzed asymmetric nitroso aldol reaction.

Uses

(S,S)-(+)-2,3-Bis(tert-butylmethylphosphino)quinoxaline is a useful reagent for organic synthesis of chiral tetraphenylenes, fused lactones and other useful intermediates.