Description
EGFR peptide is a peptide substrate of PKC that corresponds to an amino acid sequence from the intracellular region of EGFR.1 It has been used to monitor PKC activity in primary bovine retinal endothelial cells. Unlike EGFR peptide (myristoylated) (Item No. 36897), EGFR peptide does not inhibit PKC when used at a concentration of 50 µM.2WARNING This product is not for human or veterinary use.
References
[1] J Y PARK. Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation.[J]. Diabetes, 2000, 49 7: 1239-1248. DOI:
10.2337/diabetes.49.7.1239[2] C A O’BRIAN. A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to adriamycin.[J]. Investigational New Drugs, 1991, 9 2: 169-179. DOI:
10.1007/bf00175084
