Description
BAmP-O16B is an ionizable cationic amino lipid that has been used in the generation of lipid nanoparticles (LNPs).1 LNPs containing BAmP-O16B and encapsulating NSA-inactivated RNase A reduce the viability of SiHa and HeLa cancer cells, but not non-cancerous NIH3T3 and HEK293T cells, upon intracellular reactivation of RNase A by glutathione (GSH).WARNING This product is not for human or veterinary use.
References
[1] QIZHEN ZHENG Tianyu M, MING WANG* Unleashing the Power of Proenzyme Delivery for Targeted Therapeutic Applications Using Biodegradable Lipid Nanoparticles[J]. Accounts of Chemical Research, 2023, 57 2: 208-221. DOI:
10.1021/acs.accounts.3c00597
