Description
AM2201 N-
(4-
hydroxypentyl) metabolite-
d
5 contains five deuterium atoms at the 2, 4, 5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of AM2201 N-
(4-
hydroxypentyl) metabolite by GC-
or LC-
mass spectrometry. AM2201 is a potent synthetic cannabinoid (CB) with K
i values of 1.0 and 2.6 nM for the CB
1 and CB
2 receptors, respectively.
1 AM2201 N-
(4-
hydroxypentyl) metabolite is an expected urinary metabolite of AM2201, based on the known metabolism of similar compounds.
2 Its biological actions are unknown.
References
1. Makriyannis, A., and Deng, H.
Cannabimimetic indole derivatives US7241799B2,(2001).
2. Wintermeyer, A., M?ller, I., Thevis, M., et al.
In vitro phase I metabolism of the synthetic cannabimimetic JWH-018 Anal. Bioanal. Chem. 398(5),2141-2153(2010).
