Description
EY3238 is a JAK2-HDAC dual inhibitor with low nanomolar activity against JAK2 and HDAC6 while also inhibiting HDACs 2 and 10 with IC50 values below 100 nM (JAK2 IC50 = 1.4 nM); HDAC6 IC50 = 2.1 nM; HDAC2 IC50 = 49nM; HDAC10 IC50 = 80 nM.).
