Uses
Caramiphen hydrochloride has been used to test its inhibitory effect on voltage-gated Na
+ currents using the patch-clamp method.
Biochem/physiol Actions
Caramiphen hydrochloride is non-narcotic and possesses many biological functionalities of being antitussive, anticonvulsive, and neuroprotective. It induces sensory block and displays less toxicity when compared to bupivacaine. The local anesthetic functionality of caramiphen is mediated by its inhibitory effect on voltage-gated Na+ currents.
