Ontuxizumab
- Product NameOntuxizumab
- CAS946415-62-9
- CBNumberCB78080902
- MW0
- MOL FileMol file
- MSDS FileSDS
Ontuxizumab Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| ChemScene CS-0629216 | 1mg | $379 | Ontuxizumab 99.85% |
Buy |
| ChemScene CS-0629216 | 5mg | $1029 | Ontuxizumab 99.85% |
Buy |
| ChemScene CS-0629216 | 10mg | $1722 | Ontuxizumab 99.85% |
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| ChemScene CS-0629216 | 25mg | $3142 | Ontuxizumab 99.85% |
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| Biorbyt Ltd orb1290208 | 100μg | $280 | Ontuxizumab >95% |
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Ontuxizumab Chemical Properties,Usage,Production
Uses
Ontuxizumab (MORAb-004) is a humanized IgG1/κ anti-endosialin (TEM-1 or CD248) monoclonal antibody with antitumor effects. Ontuxizumab can be used for the research of cancer[1].in vivo
Ontuxizumab (50 mg/kg; i.v., 5 doses daily for 5 consecutive days) shows antitumor effects in human CD248 knock-in mice[1].
| Animal Model: | Human CD248 knock-in mice[1] |
| Dosage: | 50 mg/kg |
| Administration: | Intravenous injection via tail vein; 50 mg/kg, 5 doses daily for 5 consecutive days |
| Result: | Reduced tumor growth with a lower level of CD248 and α-SMA on neovasculature pericytes. |
References
[1] Rybinski K, et al. Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature. Oncotarget. 2015 Sep 22;6(28):25429-40. DOI:10.18632/oncotarget.4559Preparation Products And Raw materials
Ontuxizumab Suppliers
Global(19)Suppliers
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