Chemical Properties
clear colorless to slightly yellow liquid
Uses
4-Fluorophenethylamine may be employed as nucleophile in the synthesis of 2-amino-4-arylpyrimidine derivatives. It is suitable for use in the preparation of
ortho-metalated primary phenethylamines having electron-releasing and electron-withdrawing groups on the aromatic ring, leading to complexes containing six membered palladacycles.
Application
Firstly, ethyl 2-cyano-3,3-dimethythioacrylate was prepared from reactions of ethyl cyanoacetate with carbon disulfide and dimethyl sulfate. Secondly, it reacted with 4-fluorophenethylamine to yield ethyl 2-cyano-3-methythioacrylate-3-[2-(4- fluorophenyl)-ethylamino]-acrylate.
Precautions
Stable under recommended storage conditions. Incompatible with oxidizing agents and acids.
