N-Benzyl-guanidine

Uses

N-Benzylguanidine is a useful building block and has been used in the synthesis of novel substituted 2-(2-aminopyrimidin-4-yl) pyridine-4-carboxylates as potent inhibitors of JumonjiC domain-containing histone demethylases in human esophageal squamous cell carcinoma cells.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 5933, 1992 DOI: 10.1016/S0040-4039(00)61092-4