Uses
Docosyl Ferulate is a compound derived form Ferulic Acid (F308900), widely distributed in small amounts in plants. Used as an antioxidant and food preservative.
Definition
ChEBI: Docosyl trans-ferulate is a hydroxycinnamic acid. It has a role as a metabolite.
Application
Docosyl ferulate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.
Also, for use with USP monograph such as:
Pygeum Capsules
Pygeum Extract
Biological Activity
Docosyl ferulate is a protocatechuic acid analogue. It inhibits tyrosinase (an enzyme that catalyses the conversion of tyrosinase into melanin) and has anticancer activity in vitro. It inhibits the growth of cancer cells by binding to the receptor protein CXCR4 on the surface of tumour cells. The compound also inhibited angiotensin II-induced elevation of blood pressure in rats, probably due to its ability to inhibit tyrosine kinase activity. In addition, Docosyl ferulate has been shown to inhibit growth factor beta (GFβ) and cell proliferation in human skin cells.
