The flavonoid 4,4'-Dimethoxychalcone acts as an anti-ageing compound with cardioprotective effects in mice and the potential to promote longevity across species[1].
4,4'-Dimethoxychalcone (100mg/kg; intraperitoneally) efficiently triggered autophagic flux in the heart and liver from wild type (WT) C57BL/6 mice[1].
| Animal Model: | 6-week-old male wild type C57BL/6 or Atg4b-/- mice[1] |
| Dosage: | 100mg/kg |
| Administration: | Injected intraperitoneally with a single |
| Result: | Triggered autophagic flux in the heart and liver. |