Uses
Sanggenol L induces caspase-dependent and caspase-independent apoptosis in melanoma skin cancer cells[1]. Sanggenol L induces of apoptosis via suppression of PI3K/Akt/mTOR signaling and cell cycle arrest via activation of p53 in p
Definition
ChEBI: Sanggenol L is an extended flavonoid.
target
p65 | NF-kB | IkB | c-Myc | Caspase | IKK
References
[1] Won YS, Seo KI. Sanggenol L promotes apoptotic cell death in melanoma skin cancer cells through activation of caspase cascades and apoptosis-inducing factor.Food Chem Toxicol. 2020;138:111221. DOI:
10.1016/j.fct.2020.111221[2] Won YS, Seo KI. Sanggenol L Induces Apoptosis and Cell Cycle Arrest via Activation of p53 and Suppression of PI3K/Akt/mTOR Signaling in Human Prostate Cancer Cells.Nutrients. 2020;12(2):488. Published 2020 Feb 14. DOI:
10.3390/nu12020488
