Uses
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT
Procedure (sandwich, competitive & Indirect ELISA)
General Description
The Human β-NGF (β-nerve growth factor) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an
in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human β-NGF in serum, plasma, cell culture supernatants and urine.
Biochem/physiol Actions
NGFβ (nerve growth factor β ) is a potent neurotrophic factor that plays a vital role in development and maintenance of nervous systems and is essential for the differentiation and survival of neurons. It also mediates angiogenesis and facilitates progression and development of various cancer including, oral, breast and prostate cancers. Elevated expression of NGFβ contributes to progression of human cholangiocarcinoma. It has potential as marker for the diagnosis of interstitial cystitis/painful bladder syndrome (IC/PBS) and overactive bladder (OAB) and might also aid in determining the therapy for the same. It might alter placental function, as NGF signaling in placenta is influenced by antenatal depression and selective serotonin reuptake inhibitor (SSRI) treatment.
