Methyl (3E)-4-Phenylbut-3-enoate

Uses

Building block is reported by Huw Davies and coworkers as a precursor to the 2013 EROS Best Reagent; Methyl (E)-4-Phenyl-2-diazo-3-butenoate. Methyl (E)-4-Phenyl-2-diazo-3-butenoate is a donor-acceptor precursor to the corresponding Ru-carbenoid that is utilized in C-H insertion and cyclopropanation reactions.

Synthesis Reference(s)

The Journal of Organic Chemistry, 59, p. 3202, 1994 DOI: 10.1021/jo00090a043
Tetrahedron Letters, 31, p. 3757, 1990 DOI: 10.1016/S0040-4039(00)97463-X