Chemical Properties
Furan-3,4-diyldimethanol is a colorless to pale yellow liquid at room temperature, with a density of 1.248 g/mL at 25℃, a boiling point of 120℃ at 1 Torr, a flash point of >110℃, and a predicted pKa of 13.88. It is extremely weakly acidic, and its molecule contains a furan ring and two hydroxymethyl groups. It is readily soluble in most organic solvents such as alcohols and ethers, miscible with water, and chemically stable. The hydroxyl groups can undergo esterification, etherification, oxidation, and other reactions. It is an important intermediate in the fields of organic synthesis, medicine, and functional materials.
Uses
3,4-Furandimethanol has been used as a reactant in the preparation of N-[(benzimidazolyl)methyl]aminotetrahydroquinoline derivatives as CXCR4 antagonists that are potent inhibitors of T tropic (X4) HIV-1 replication.
