Description
(±)5(6)-EET-d11 methyl ester is intended for use as an internal standard for the quantification of 5(6)-EET methyl ester by GC- or LC-MS. (±)5(6)-EET methyl ester (Item No. 50210) is an esterified form of (±)5(6)-EET (Item No. 50211). 5(S),6(R)-EET and 5(R),6(S)-EET are formed via epoxidation of arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) by a variety of cytochrome P450 (CYP) isoforms, including CYP2B1, CYP2B2, CYP2C11, CYP2C23, and CYP2C24.1,2WARNING This product is not for human or veterinary use.
References
[1] ARTHUR A SPECTOR A W N. Action of epoxyeicosatrienoic acids on cellular function.[J]. American journal of physiology. Cell physiology, 2007, 292 3: C996-1012. DOI:
10.1152/ajpcell.00402.2006[2] J H CAPDEVILA R C H J R Falck. Cytochrome P450 and arachidonic acid bioactivation. Molecular and functional properties of the arachidonate monooxygenase.[J]. Journal of Lipid Research, 2000, 41 2: 163-181.
