Amorphadiene

Uses

Amorphadiene is a sesquiterpene synthesized via the cyclization of farnesyl pyrophosphate and a precursor in the biosynthesis of??Artemisinin (A777500), which is an effective antimalarial agent used to treat malaria. Genetically modified Saccharomyces cerevisiae can be utilized as an alternative semisynthetic strategy to produce artemisinin from amorphadiene.

Definition

ChEBI: Amorpha-4,11-diene is a sesquiterpene and a member of octahydronaphthalenes.