mPEG11-Br
- Product NamemPEG11-Br
- CAS1258596-39-2
- CBNumberCB63340213
- MFC23H47BrO11
- MW579.52
- MDL NumberMFCD31656939
- MOL File1258596-39-2.mol
Chemical Properties
Boiling point | 564.5±45.0 °C(Predicted) |
Density | 1.179±0.06 g/cm3(Predicted) |
mPEG11-Br Chemical Properties,Usage,Production
Biological Activity
m-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562Preparation Products And Raw materials
mPEG11-Br Suppliers
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