Description
(±)-LY426965 is a racemic mixture of the serotonin (5-HT) receptor subtype 5-HT
1A antagonist (S)-(+)-LY426965 and (R)-(–)-LY426965.
1,2
References
1. Kaplin, A.I., Hendrix, C.W., and Rahn, K.A.
Methods for reducing anxiety and impulsivity in subjects initiating treatment with serotonin reuptake inhibitors WO2014209991A1,(2014).
2. Denmark, S.E., and Fu, J.
Asymmetric construction of quaternary centers by enantioselective allylation: Application to the synthesis of the serotonin antagonist LY426965 Org. Lett. 4(11),1951-1953(2002).
