![UNC3230 Structure](https://www.chemicalbook.com/CAS/20180713/GIF/1031602-63-7.gif)
UNC3230
- Product NameUNC3230
- CAS1031602-63-7
- CBNumberCB63067589
- MFC17H20N4O2S
- MW344.43
- MDL NumberMFCD15031190
- MOL File1031602-63-7.mol
Chemical Properties
storage temp. | Store at -20°C |
solubility | DMSO:30.0(Max Conc. mg/mL);87.1(Max Conc. mM) DMF:30.0(Max Conc. mg/mL);87.1(Max Conc. mM) Ethanol:0.2(Max Conc. mg/mL);0.58(Max Conc. mM) |
form | A crystalline solid |
UNC3230 Price
Product number | Packaging | Price | Product description | Buy |
---|---|---|---|---|
Cayman Chemical 16401 | 1mg | $48 | UNC3230 ≥95% |
Buy |
Cayman Chemical 16401 | 5mg | $117 | UNC3230 ≥95% |
Buy |
Cayman Chemical 16401 | 10mg | $210 | UNC3230 ≥95% |
Buy |
Cayman Chemical 16401 | 50mg | $807 | UNC3230 ≥95% |
Buy |
Tocris 5271 | 50 | $844 | UNC3230 ≥99%(HPLC) |
Buy |
UNC3230 Chemical Properties,Usage,Production
Description
Phosphatidylinositol-4-phosphate 5-kinase type-1 γ (PIP5K1C) is a lipid kinase that generates phosphatidylinositol-4,5-bisphosphate (PIP2) in nociceptive dorsal root ganglia (DRG). Pain sensitization is regulated by multiple signaling pathways that are initiated by phospholipase C-mediated hydrolysis of PIP2. UNC3230 is a small molecule inhibitor of PIP5K1C (IC50 = 41 nM, Kd = 51 nM). It does not inhibit any other lipid kinases that regulate phosphoinositide levels, including phosphatidylinositol 3-kinases. At 100 nM, UNC3230 decreases PIP2 membrane levels in cultured DRG neurons by 45% and significantly reduces calcium signaling. At 2 nM, it displays antinociceptive effects in mouse models of chronic pain when administered intrathecally or injected into inflamed hindpaw.Uses
UNC 3230 is a potent inhibitor of PIP5K1C.storage
Store at +4°CPreparation Products And Raw materials
UNC3230 Supplier
Global(47)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
+undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 | |
+1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 | |
+1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 | |
+1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 | |
+86-19164747840 +86-13119157289 |
13119157289@163.com | China | 2971 | 58 | |
+1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 | |
571-89925085 | sales@amadischem.com | China | 131980 | 58 | |
021-58170097 | info@topbiochem.com | China | 9457 | 58 | |
+86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 | |
021-65675885 18964387627 |
info@efebio.com | China | 9708 | 58 |
UNC3230 Spectrum
1031602-63-7, UNC3230Related Search
PROMPT×
PROMPT
The What'sApp is temporarily not supported in mainland China
The What'sApp is temporarily not supported in mainland China
Cancel
Determine