Description
1,2-
Dipalmitoyl-
sn-
glycero-
O-
ethyl-
3-
PC is a phospholipid containing the saturated long-
chain (16:0) stearic acid inserted at the
sn-
1 and
sn-
2 positions and an alkyl group on the phosphate oxygen of the polar headgroup. Cationic phospholipids such as this have proved useful as DNA transfection agents and for studies of surface charge density within lipid bilayers.
Uses
16:0 EPC chloride, a P-O-ethyl derivative, is a saturated cationic lipid. 16:0 EPC chloride can serve as a DNA and RNA transfecting agent. 16:0 EPC chloride can be used as a co-adjuvant for preparing vaccines and promote drug delivery[1].
References
[1] Pungente M . Correlation Of Lipoplex Morphology And Transfection Efficacy For Pyridinium-Based Cationic Lipids By Means Of Synchrotron Small Angle X-Ray Diffraction. 2013.
