N-(3,4-dimethoxyphenyl)ethanamide

Uses

N-(3,4-Dimethoxyphenyl)acetamide is an intermediate used in the synthesis of 5,6-Orthoquinone Primaquine-d6 Hydrobromide (O697512), which is an isotope labeled compound of 5,6-Orthoquinone Primaquine (O697510). 5,6-Orthoquinone Primaquine is used in the study of the differential pharmacological and toxicological properties of primaquine enantiomers. Primaquine is currently the only approved drug for the treatment and radical cure of Plasmodium vivax malaria.

Synthesis Reference(s)

The Journal of Organic Chemistry, 59, p. 5814, 1994 DOI: 10.1021/jo00098a050