(7R)-6,7,7a,8-Tetrahydro-7-acetyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline

Description

Anemonin, a naturally occurring selective iNOS inhibitor, it has potential anti-inflammatory effect. Anemonin is a potent protective molecule for osteoarthritis, it delays osteoarthritis progression by suppressing ECM loss and chondrocyte hypertrophy partially by suppressing IL-1β/NF-κB pathway activation. 3. Anemonin can alleviate nerve injury after cerebral ischemia and reperfusion (i/r) in rats by improving antioxidant activities and inhibiting apoptosis pathway. 4. Anemonin inhibits melanin synthesis by inhibiting the transcription of the genes encoding MITF, TYR, TRP1, and TRP

Definition

ChEBI: N-Acetylanonaine is an isoquinoline alkaloid.

target

NOS | IL Receptor | NF-kB | MMP(e.g.TIMP)