Uses
CP 96345 is a potent and selective non-peptide NK1 receptor antagonist (1,2,3). CP 96345 attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo.
Uses
CP 96345 is a potent and selective non-peptide NK1 receptor antagonist. CP 96345 attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo.
Biological Activity
Potent and selective non-peptide NK 1 receptor antagonist. Attenuates substance P-induced salivary response and inhibits neurogenic inflammation in vivo .
Biochem/physiol Actions
CP-96345 is a selective NK1 antagonist. CP96345 inhibits substance P-induced salivation in the rat by classical in vivo bioassay, but did not inhibit NK2, NK3, or numerous other receptors.
