2H-Pyrano[2,3-b]quinoline, 3,4-dihydro-2,5,6,8-tetramethyl-

Uses

The Yu Fluorination Ligand in tandem with Selectfluor(R) (Aldrich 439479) under palladium catalysis can promote direct fluorination of C(sp³)-H bonds stereoselectively. Yu and coworkers have displayed this on amino acid derivatives with directing group assistance from the Yu-Wasa Auxiliary (Aldrich 791806).

General Description

Yu Fluorination Ligand is widely employed for the chemoselective functionalization of sp²- and sp³ C-H bonds.