MEVASTATIN, SODIUM SALT

Uses

Carboxylate form of Mevastatin that is active in whole cells and in cell-free assays.
Carboxylate form of Mevastatin that is active in whole cells and in cell-free assays. Mevastatin is an antibiotic that acts as a potent inhibitor of HMG-CoA reductase. Suppresses Ras farnesylation and inhibits myoblast fusion. Causes cell cycle arrest in late G₁ phase. Mevastatin may also induce bone morphogenic protein-2 (BMP-2).

Biological Activity

Cell permeable: no', 'Primary Target
HMG-CoA reductase', 'Product does not compete with ATP.', 'Reversible: no