Uses
An isotopically labeled analog of retinoic acid. Physiological metabolite of vitamin A. Effects gene expression via nuclear retinoic acid receptors (RAR); mediates cellular growth and differentiation.
A representative lot contains 11% d4, no d0 o
Uses
An isotopically Labelled analog of retinoic acid. Physiological metabolite of vitamin A. Effects gene expression via nuclear retinoic acid receptors (RAR); mediates cellular growth and differentiation.
A representative lot contains 11% d4, no d0 or d1 pr
References
[1] NADIA IDRES. Activation of retinoic acid receptor-dependent transcription by all-trans-retinoic acid metabolites and isomers.[J]. Psychological Inquiry, 2002, 4 1: 31491-31498. DOI:
10.1074/jbc.m205016200[2] A K VERMA. Inhibition of skin tumor promotion by retinoic acid and its metabolite 5,6-epoxyretinoic acid.[J]. Cancer research, 1980, 40 7: 2367-2371.
[3] SHI-YING CAI. All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice.[J]. Journal of Pharmacology and Experimental Therapeutics, 2014, 349 1: 94-98. DOI:
10.1124/jpet.113.209353[4] SEONG CHUL KIM. All-trans-retinoic acid ameliorates hepatic steatosis in mice by a novel transcriptional cascade[J]. Hepatology, 2013, 59 5: 1750-1760. DOI:
10.1002/hep.26699
