Uses
CEP-40125 (RXDX-107) is a modified form of Bendamustine (HY-13567), a DNA cross-linking agent that may cause DNA damage and cell apoptosis. CEP-40125 (RXDX-107) is formed by encapsulating the alkyl ester form of Bendamustine in human serum albumin[1][2].
References
[1] Pharmaceutical prodrugs and methods of their preparation and use. WO2018013783.
[2] Croasdell G. The 34th Annual JP Morgan Healthcare Conference. San Francisco, California, USA-January 11-14, 2016[J]. Drugs of the Future, 2016, 41(1).
