Azido-PEG3-aldehyde
- Product NameAzido-PEG3-aldehyde
- CAS1807530-10-4
- CBNumberCB53062350
- MFC9H17N3O4
- MW231.25
- MDL NumberMFCD28976706
- MOL File1807530-10-4.mol
Azido-PEG3-aldehyde Chemical Properties,Usage,Production
Biological Activity
Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562Preparation Products And Raw materials
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