RSV604
- Product NameRSV604
- CAS676128-63-5
- CBNumberCB53041458
- MFC22H17FN4O2
- MW388.39
- MDL NumberMFCD28963952
- MOL File676128-63-5.mol
Chemical Properties
| storage temp. | Store at -20°C |
| solubility | DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:20): 0.04 mg/ml; DMSO: 20 mg/ml; Ethanol: 5 mg/ml |
| form | A solid |
| FDA UNII | 6NF9HI6D98 |
RSV604 Price
| Product number | Packaging | Price | Product description | Buy |
|---|---|---|---|---|
| Cayman Chemical 29041 | 5mg | $100 | RSV-604 |
Buy |
| Cayman Chemical 29041 | 25mg | $381 | RSV-604 |
Buy |
| Cayman Chemical 29041 | 1mg | $32 | RSV-604 |
Buy |
| Cayman Chemical 29041 | 10mg | $184 | RSV-604 |
Buy |
| AK Scientific 8549CN | 5mg | $209 | 1-(2-Fluorophenyl)-3-[(3S)-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepin-3-yl]urea |
Buy |
RSV604 Chemical Properties,Usage,Production
Biological Activity
RSV604 (A-60444), a novel benzodiazepine, is an inhibitor of respiratory syncytial virus (RSV) with EC50 of 0.86 μM. It has the potential to treat RSV-related diseases. Phase 2.in vitro
RSV604 (5 days) inhibits the growth of four laboratory strains of RSV (RSS, Long, A2 and B), with EC 50 s ranging from 0.5 to 0.9 μM in plaque reduction assay.
It (6 days) inhibits RSV-induced HEp-2 cell death, with an EC 50 of 0.86 μM.
Also RSV604 (3 days) reduces viral antigen synthesis in RSV-infected HEp-2 cells, with an EC 50 of 1.7 μM.
RSV604 (1-20 μM; 7 days) dose-dependently inhibits RSV infection in human airway epithelial (HAE) cells, with no gross cytotoxicity, leakage of basolateral fluid to the apical surface, or alteration of cilium beat frequency.
target
| Target | Value |
| RSV (Cell-free assay) | 0.86 μM(EC50) |
Preparation Products And Raw materials
RSV604 Supplier
Global(63)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 | |
| +86-0371-86658258 15093356674; |
laboratory@coreychem.com | China | 30255 | 58 | |
| +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 | |
| +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 | |
| +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 | |
| 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 | |
| +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 | |
| 571-89925085 | sales@amadischem.com | China | 131981 | 58 | |
| 1-631-485-4226; 16314854226 |
info@bocsci.com | United States | 14059 | 65 | |
| 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
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