Anti-GCA antibody produced in chicken

Uses

Anti-GCA antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biological Activity

Grancalcin is a protein encoded by the GCA gene in humans and is a member of the EF-hand family of calcium-binding proteins called PEF proteins. It is a EF-hand Ca2+-binding protein (28kDa) particularly abundant in neutrophils and monocytes, with relatively small amounts in lymphocytes. Grancalcin consists of four EF-hand calcium-binding motifs and exhibits strong homology to sorcin, one of two proteins overexpressed in multidrug-resistant cells.