(2S,4S)-1-fMoc-4-azidopyrrolidine-2-carboxylic acid

Chemical Properties

White crystalline powder

General Description

A useful tool for the synthesis of branched, side-chain modified and cyclic peptides by Fmoc SPPS. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols [1] or phosphines [2, 3].

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis