Uses
Ethyl 2-bromooxazole-5-carboxylate is an organic synthesis intermediate. In the synthesis of novel topoisomerase II inhibitors (such as IID432), this compound serves as a coupling substrate for the construction of the oxazole ring core structure [1].
References
[1] Olivier René, Manuel Saldivia, Maxime Dauphinais, et al. (2026). Discovery of IID432 for Chagas Disease: A Cyanotriazole Inhibitor of Trypanosoma cruzi Topoisomerase II Achieves Sterile Cure After Short-Term Treatment in a Chronic Infection Model. Journal of medicinal chemistry, 69(2), 1135–1153. https://doi.org/
10.1021/acs.jmedchem.5c02459
