Description
Mitragyna ciliata Aubr. et Pellegr. yields this carboline alkaloid which may be
purified by crystallization from Et20-light petroleum when it forms small,
colourless crystals. The ultraviolet spectrum exhibits absorption maxima at 228
and 292.4 mil with shoulders at 248.8 and 284 mil. The base may be charac_x0002_terized as the perchlorate which forms light yellow prisms from EtOH-Et20,
m.p.229-230°C.
References
[1] Beckett, Shellard, Tackie., J. Pharm. Pharmacal. Suppl., 15, 166T (1963)
[2] Beckett, Tackie., ibid, 15, 267T (1963)
[3] Absolute configuration: Lee, Trager, Beckett., Tetrahedron, 23, 375 (1967)
[4] [1] ANIKA A. PHILIPP . Metabolism studies of the Kratom alkaloids mitraciliatine and isopaynantheine, diastereomers of the main alkaloids mitragynine and paynantheine, in rat and human urine using liquid chromatography–linear ion trap-mass spectrometry[J]. Journal of Chromatography B, 2011, 879 15: Pages 1049-1055. DOI:
10.1016/j.jchromb.2011.03.005[5] [2] SOUMEN CHAKRABORTY. Kratom Alkaloids as Probes for Opioid Receptor Function: Pharmacological Characterization of Minor Indole and Oxindole Alkaloids from Kratom[J]. ACS Chemical Neuroscience, 2021, 12 14: 2661-2678. DOI:
10.1021/acschemneuro.1c00149
